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Toggle navigation. Figure 1. He observed a variable spectrum of small aneurysms and dilated capillaries with sub- and intra-retinal fluid and exudate accumulation in young male patients. This process may progress to involve the posterior pole, causing substantial vision loss in advanced cases.
Mean age at presentation was 47 years. The bilateral presentation emphasizes the need for regular follow-up to detect possible future involvement of the fellow eye. Most of the reports exist in the form of isolated case reports or small case series.
Coats disease is a telangiectatic neovascular disease of the retina of unknown etiology that frequently affects unilateral eyes of young males. George Coats  in described the histopathological features of enucleated eyes with massive exudation. He divided the morphology into 3 groups:. A large study of patients  took the definition of Coats disease as 'idiopathic retinal telangiectasia and intraretinal or subretinal exudation without appreciable signs of vitreoretinal traction.